Instead of all round, flexible red blood cells that transport oxygen easily, people with sickle cell disease have rigid, concave cells shaped like sickles used to harvest grain.
A single gene mutation is responsible for the sickle cell trait. Find out who is prone to sickle cell disease, often called sickle cell anemia, although anemia is only one of the symptoms.
A gene that causes a deadly disease must be broken, right? Wrong. It turns out the gene responsible for sickle cell disease has spread to millions of people because it saves lives. Take a look at Tony Allison's work. More...
People with sickle cell disease often have anemia, a shortage of red blood cells and/or the hemoglobin inside them. To make matters worse, their red blood cells have shorter life spans. More...
Play this game show quiz to test your knowledge of sickle cell disease. Answer all the questions for the chance to slime the host. Beware the slimebuster cards!
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Teen life is challenging, teen life with sickle cell even more so. But close attention to diet, exercise, medication — and symptoms — can maintain health. Theresa explains it all. More...
If you thought vanilla was just for flavoring foods and beverages, think again. Listen as a hematologist Dr. Toshio Asakura explains a promising sickle cell disease treatment using a vanilla compound. More...
Beta thalassemia trait is a genetic mutation that affects production of hemoglobin in the blood. When one parent has this trait and the other has the sickle cell trait, their child could have this doubly serious disorder. More...
Football can be a dangerous sport, no matter what. But people born with sickle cell trait have to be extra-cautious when playing hard. Why? More...
Sickle cell anemia is a genetic disorder caused by a single change in the DNA strand. This animated video shows how one letter “misspelling” is all it takes to trigger this condition. More...
When you think you’re ready, take this 10-question test about sickle cell disease. It’s true/false, so you have a 50-50 chance of being right, even if you guess! More...
Slow, medium, or fast sickling? When red blood cells dump oxygen and start to sickle, becoming long and rigid, which speed produces the most damage? Get the answer here. More...